Success Rates


Our clinic has been in existence for almost a quarter of a century (established 1993)

Over the past 23 years, we have helped more than thousands of infertile couples to have a baby / babies

The clinic excels in the management of all categories of male and female factor infertility. It also has one of the largest "Third party ART" programs (oocyte, sperm, embryo donation and surrogacy)

More than a thousand couples fulfil their dreams at our clinic every year (since 2011)

We maintain success rates for various procedures on par with the best clinics in the world

TECHNIQUE CLINICAL PREGNANCY RATE (%)
Intrauterine Insemination (IUI) 24%
In vitro fertilization (IVF) 44%
Intracytoplasmic sperm injection (ICSI) 42%
Egg (oocyte) donation (OD) 54%
Embryo donation (ED) 66%
Gestational surrogacy (own eggs) 44%
Gestational surrogacy (donor eggs) 68%

Recent Advances and Trends

Currently, the clinic is on the verge of a major shift in policy towards "FREEZE ALL". This means that we would stimulate the ovaries, retrieve the eggs, fertilize them and freeze all the embryos. Embryo transfer would NOT be done in the stimulation cycle (NO FRESH EMBRYO TRANSFER). In the subsequent month, the uterus is primed with appropriate medication to improve its receptivity and frozen embryos are transferred once this is achieved.

Conventional IVF with fresh embryo transfer has failed to exceed success rates of 40% over the past two decades. This is due to the suboptimal "readiness" of the uterus (endometrium) in 60% of patients (as a side effect of the injections given to produce multiple eggs). With the advent of the new technique of "vitrification" embryos can now be frozen and preserved safely (without any risk of damage by the freezing procedure). As a result of these two advances we are now able to optimize and increase success rates to around 50% per cycle. The cycle, of course, would now be of two months instead of the conventional one month. This is particularly advantageous in the following situations:

  • Less eggs and embryos (less than 3 embryos of grade 1).
  • Patients with low AMH and poor responders (pooling of embryos).
  • History of previous miscarriage / biochemical pregnancy
  • History of previous ectopic pregnancy.
  • Retrieval of more than 20 eggs (to avoid ovarian hyperstimulation).
  • Endometrium (uterus lining) thin or < 7 mm in thickness.
  • History of previous IVF failures
  • Abnormal hormone levels (elevated progesterone) in the stimulation cycle
  • Patients with polycystic ovaries
  • Patients with endometriosis

IVF success rates have been quite steady for more than two decades now. With “Fresh” embryo transfer (transfer in the same cycle as the egg retrieval) pregnancy rates were in the range of @ 40-45% and after correcting for pregnancy losses and miscarriages, the net take home baby was in the range of 37-40%

Over the past two years, our centre made a gradual shift in policy towards “freeze-all embryos” in tune with some of the leading IVF clinics in the world. This means that in the first cycle we perform the egg retrieval followed by IVF/ICSI and freezing of all the embryos (no fresh embryo transfer). In the next cycle (month) the uterus and its lining (endometrium) are optimally prepared and embryo transfer is performed using “frozen” embryos. With this approach, we ensure that embryos are transferred into a more receptive uterus. Did it work?

Here is some data from our clinic for the last five months (January to May 2015). Please note that these are patients undergoing IVF using their own eggs, sperms and uterus. These statistics do not include patients of egg donation, embryo donation and surrogacy where success rates are obviously much higher

Pregnancy rate 53%
Missed abortion rate 3.6%
Biochemical pregnancy rate 2.2%
Tubal (ectopic pregnancy rate) 0.4%
Ongoing pregnancy rate 49.4%

This shows a clear 10% increase in pregnancy rates (especially ongoing pregnancies indicating a reduction in the number of miscarriages and other early pregnancy losses). This increase in pregnancy rate is due to a better state of “preparedness” of the womb to accept the embryo. In the fresh cycle, we cannot administer hormones or other medicines to improve the receptivity of the endometrium (thickness and quality) as these would interfere with the egg quality. This is easily done in the next month which is why the pregnancy rates are much higher with frozen embryos

To our mind, this is one of the most significant advances in the field of IVF technology resulting in a remarkable increase in pregnancy rates as compared to conventional IVF with fresh embryo transfer. Of course, we need more data and more international publications demonstrating similar results before advocating it as standard practice

How did we do?

2015-2016

For IVF & ICSI (Fresh and frozen embryo transfer in 2015, only frozen embryo transfer in 2016)

IVF 47%
ICSI 45%

For other categories:

Egg donation with IVF / ICSI 62%
Embryo Donation 67%
IUI (Husband’s sperm) 22%
IUI (Donor sperm) 26%
Own eggs with surrogacy 42%
Donor eggs with surrogacy 64%
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